Expression of the hematopoietic growth factor receptor FLT3 (STK- 1/Flk2) in human leukemias
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منابع مشابه
Expression of the Hematopoietic Growth Factor Receptor FLT3 (STK-UFIk2) in Human Leukemias
Normal expression of the hematopoietic growth factor receptor FLT3 (STK-lIIFIkZ) is limited t o CD34+ stem/progenitor cells. We have evaluated the expression of FLTB by RNase protection assay and Western blotting in 161 primary bone marrow (BM) samples from patients with leukemia. FLTB RNA was found t o be expressed at a higher level than in normal BM controls in 33 of 33 B-lineage acute leukem...
متن کاملExpression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias.
Normal expression of the hematopoietic growth factor receptor FLT3 (STK-1@Flk2) is limited to CD34+ stem/progenitor cells. We have evaluated the expression of FLT3 by RNase protection assay and Western blotting in 161 primary bone marrow (BM) samples from patients with leukemia. FLT3 RNA was found to be expressed at a higher level than in normal BM controls in 33 of 33 B-lineage acute leukemias...
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متن کاملExpression of the Hematopoietic Growth Factor Receptor FLT 3 (
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Background and Objective: Vascular endothelial growth factor (VEGF) is a cytokine which is overexpressed in many malignant cancers including leukemia. VEGF plays an important role in tumor invasion and metastasis. Determination of the pattern of VEGF expression in human leukemic cell lines could be useful not only in screening of new antileukemic agents but also to study the mechanism of their ...
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ژورنال
عنوان ژورنال: Blood
سال: 1996
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v87.3.1089.bloodjournal8731089